What is the Liver Life Challenge?

The Liver Life Challenge is the American Liver Foundation’s official endurance program, where dedicated athletes across the country use their passion and commitment to go the extra mile for the liver community.

Fundraising and participation in our Liver Life Challenge events bring awareness to liver disease and provide financial support for our educational programs and patient services offered to the millions of Americans battling one of the 100 known liver diseases.

Choose Your Challenge:


Bank of America Chicago Marathon


Boston Marathon

New York City

TCS New York City Marathon


Take the 45 in 45 Challenge from wherever you are!

Choose Your Own

Choose your own race and fundraise for ALF

Meet our 2020 National LIVEr Champions, Deb and Keith Tully

Deb and Keith Tully have run over 20 Boston Marathons® beginning in 2007 when Keith ran his first Marathon and Deb soon got the marathon bug.

Around that same time, as part a routine physical exam, Keith learned that his liver function tests were elevated. He was diagnosed with Primary Sclerosing Cholangitis (PSC), a rare autoimmune liver disease that currently has no cure and will ultimately require a liver transplant for survival. It wasn’t long after that the Tully family found the American Liver Foundation’s Boston Marathon® Team, which provided an opportunity to raise awareness and funds for liver disease research and advocacy efforts.

The Tully Family, who together have raised more than $465,000, the ALF New England Division offers a community like no other full of people who have been touched in some way by liver disease, all focused on finding a cure, breaking the stigma and making a difference to patients and families living with liver disease.